{"id":3715,"date":"2022-07-18T06:32:52","date_gmt":"2022-07-18T06:32:52","guid":{"rendered":"https:\/\/thepafp.org\/journal\/?post_type=abstract&p=3715"},"modified":"2022-07-18T06:32:52","modified_gmt":"2022-07-18T06:32:52","slug":"treatment-decisions-based-on-clinical-trials","status":"publish","type":"abstract","link":"https:\/\/thepafp.org\/journal\/abstract\/treatment-decisions-based-on-clinical-trials\/","title":{"rendered":"Treatment Decisions Based on Clinical Trials"},"content":{"rendered":"

Treatment Decisions Based on Clinical Trials<\/h2><\/div>

Abigael C. Andal-Saniano, MD, FÂ鶹ֱ²¥ and Maria Kristina Ibarra Marquez, MD<\/p>\n<\/div><\/div><\/div>

View Full Text<\/span><\/a><\/div><\/div><\/div><\/div><\/div>

The randomized Controlled Trial is the standard design to prove the effectiveness of drugs or other forms of interventions. In this type of clinical research, individuals are randomly assigned (randomization) to either of the two or more groups, one with the intervention the other without the intervention being tested or another intervention. When done properly, it can provide the best evidence of effectiveness.<\/p>\n

Appraisal<\/strong><\/p>\n

Relevance <\/em><\/p>\n

    \n
  1. Is the objective of the article comparing therapeutic interventions similar to the clinical dilemma?<\/li>\n<\/ol>\n

    Validity <\/em><\/p>\n

      \n
    1. Was the assignment of patients to treatment randomized?<\/li>\n
    2. Were all patients who entered the trial properly followed-up and attributed at its conclusion?<\/li>\n
    3. Were patients analyzed in the groups to the they were randomized, or an intention-to-treat analysis done?<\/li>\n
    4. Were patients, their clinicians, and study personnel \u201cblind\u201d to treatment?<\/li>\n
    5. Were the groups similar at the start of the trial?<\/li>\n<\/ol>\n

      Results <\/em><\/p>\n

        \n
      1. How large was the treatment effect?<\/li>\n
      2. Was the treatment effect statistically significant?<\/li>\n<\/ol>\n

        Applicability <\/em><\/p>\n

          \n
        1. Can the results be applied to my patient care?<\/li>\n
        2. Was the outcome considered clinically important?<\/li>\n
        3. Are the likely treatment benefits worth the potential harm?<\/li>\n<\/ol>\n

          Key words<\/strong>: Evidence-based family practice, treatment, randomized controlled trials<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"footnotes":""},"categories":[14,23],"tags":[16],"class_list":["post-3715","abstract","type-abstract","status-publish","hentry","category-abstract","category-abstract-2022-volume-60-issue1","tag-abstract"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/abstract\/3715","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/abstract"}],"about":[{"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/types\/abstract"}],"version-history":[{"count":2,"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/abstract\/3715\/revisions"}],"predecessor-version":[{"id":3717,"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/abstract\/3715\/revisions\/3717"}],"wp:attachment":[{"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/media?parent=3715"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/categories?post=3715"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/tags?post=3715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}