  {"id":3192,"date":"2022-03-08T08:05:32","date_gmt":"2022-03-08T08:05:32","guid":{"rendered":"https:\/\/thepafp.org\/journal\/?post_type=abstract&#038;p=3192"},"modified":"2022-03-08T08:50:05","modified_gmt":"2022-03-08T08:50:05","slug":"clinical-pathway-for-the-management-of-uninvestigated-dyspepsia-among-adults-in-family-and-community-practice-updated-2021","status":"publish","type":"abstract","link":"https:\/\/thepafp.org\/journal\/abstract\/clinical-pathway-for-the-management-of-uninvestigated-dyspepsia-among-adults-in-family-and-community-practice-updated-2021\/","title":{"rendered":"Clinical Pathway for the Management of Uninvestigated Dyspepsia among Adults in Family and Community Practice: Updated 2021"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:30px;--awb-padding-right:0px;--awb-padding-bottom:0px;--awb-padding-left:0px;--awb-margin-top:0px;--awb-margin-bottom:0px;--awb-background-color:#ffffff;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-justify-content-space-between fusion-flex-content-wrap\" style=\"max-width:calc( 1200px + 10px );margin-left: calc(-10px \/ 2 );margin-right: calc(-10px \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:80%;--awb-margin-top-large:0px;--awb-spacing-right-large:5px;--awb-margin-bottom-large:10px;--awb-spacing-left-large:5px;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:5px;--awb-spacing-left-medium:5px;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:5px;--awb-spacing-left-small:5px;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#333333;--awb-margin-top:0px;--awb-margin-bottom:10px;\"><h2 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:31;line-height:1.2;\">Clinical Pathway for the Management of Uninvestigated Dyspepsia among Adults in Family and Community Practice: Updated 2021<\/h2><\/div><div class=\"fusion-text fusion-text-1\" style=\"--awb-font-size:16px;--awb-line-height:1.2;--awb-text-transform:none;--awb-text-color:#666666;--awb-margin-top:0px;--awb-text-font-family:Georgia, serif;--awb-text-font-style:normal;--awb-text-font-weight:400;\"><p>Nenacia Ranali Nirena P. Mendoza MD, FÂé¶¹Ö±²¥, Noel M. Espallardo, MD, MSc, FÂé¶¹Ö±²¥, Anna Guia O. Limpoco, MD, FÂé¶¹Ö±²¥, Jane Efflyn Lardizabal-Bunyi, MD, FÂé¶¹Ö±²¥, Abigael C. Andal-Saniano, MD, FÂé¶¹Ö±²¥, Ma. Elinore Alba-Concha, MD, FÂé¶¹Ö±²¥, Ma. Teresa Tricia G. Bautista, MD, FÂé¶¹Ö±²¥ and Rhodora F. Pesebre, MD, FÂé¶¹Ö±²¥<\/p>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion-flex-column\" style=\"--awb-padding-top:30px;--awb-padding-right:30px;--awb-padding-bottom:30px;--awb-padding-left:30px;--awb-bg-size:cover;--awb-border-color:var(--awb-color2);--awb-border-top:1px;--awb-border-right:1px;--awb-border-bottom:1px;--awb-border-left:1px;--awb-border-style:solid;--awb-width-large:20%;--awb-margin-top-large:10px;--awb-spacing-right-large:5px;--awb-margin-bottom-large:10px;--awb-spacing-left-large:5px;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:5px;--awb-spacing-left-medium:5px;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:5px;--awb-spacing-left-small:5px;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div style=\"text-align:center;\"><a class=\"fusion-button button-flat fusion-button-default-size button-custom fusion-button-default button-1 fusion-button-span-yes \" style=\"--button_accent_color:#ffffff;--button_accent_hover_color:#ffffff;--button_border_hover_color:#781010;--button-border-radius-top-left:0;--button-border-radius-top-right:0;--button-border-radius-bottom-right:0;--button-border-radius-bottom-left:0;--button_gradient_top_color:#e6b733;--button_gradient_bottom_color:#e6b733;--button_gradient_top_color_hover:var(--awb-color4);--button_gradient_bottom_color_hover:var(--awb-color4);--button_font_size:12px;--button_typography-font-family:Arial, Helvetica, sans-serif;--button_typography-font-style:normal;--button_typography-font-weight:400;\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/thepafp.org\/journal\/wp-content\/uploads\/2022\/03\/Âé¶¹Ö±²¥-Journal_July_December-59-2-2021-pages-59-74.pdf\"><span class=\"fusion-button-text\">View Full Text<\/span><\/a><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-right:0px;--awb-padding-left:0px;--awb-margin-top:0px;--awb-margin-bottom:50px;--awb-background-color:#ffffff;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:10px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:10px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-2\" style=\"--awb-text-transform:none;\"><p><strong>Background<\/strong><\/p>\n<p>Uninvestigated dyspepsia is a common complaint in family practice in the Philippines.\u00a0 Patients usually seek consult due to severity of symptoms which affect their quality of life.\u00a0 The goals of management are short- and long-term symptom control, with reversal of possible underlying mechanisms, achievable through a combination of pharmacologic and non-pharmacologic interventions.<\/p>\n<p><strong>Objective<\/strong><\/p>\n<p>The main objective of this pathway is to guide family physicians and primary care physicians in the assessment, diagnosis and management of adult patients with uninvestigated dyspepsia through a shared decision-making process.<\/p>\n<p><strong>Method<\/strong><\/p>\n<p>This clinical pathway is an update of the Âé¶¹Ö±²¥\u2019s Clinical Pathways for the Management of Dyspepsia in Adults (2016).\u00a0 The current panel utilized the ADAPTE method and prioritized reviewing relevant clinical practice guidelines from 2017 to present. Grading of recommendation was achieved through a mixture of strength of available evidence and a consensus from a panel of experts.<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong>Summary of Recommendations<\/strong><\/p>\n<p>The main changes in the recommendations in this update are as follows: symptom-based classification of dyspepsia, screening for anxiety and depression, family and SCREEM assessment; initiation of therapeutic trial for most patients to whom <em>H. pylori<\/em> testing is not available; extension of initial PPI treatment to 4-8 weeks, consideration of antacids\/alginates for immediate symptom relief, consideration of tricyclic antidepressants for non-responders to initial treatment; symptom-based non-pharmacologic advice, consideration of counseling and other psychosocial interventions; empowerment for self-treatment and as-needed therapy for those who have completed the initial treatment regimen.<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<table style=\"padding: 5px 5px 5px 5px; height: 1203px; border: 1px solid #999999;\" width=\"1111\">\n<tbody>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" colspan=\"2\" width=\"100%\"><strong><em>History and Physical Examination<\/em><\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">1<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Obtain clinical history focusing on predominant symptoms and classify the patient into one of four symptom-based categories: ulcer-like, dysmotility-like, reflux-like, or unspecifed dyspepsia <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">2<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Elicit alarm features <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\">3<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Determine use of medication such as NSAIDs, and lifestyle practices <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">4<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Screen for anxiety or depression <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">5<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Do Family and SCREEM assessment <strong>(A-III)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">6<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Perform a focused physical examination (general survey, BMI, abdominal and rectal exam, and pelvic exam for females <strong>(A-III)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" colspan=\"2\" width=\"100%\"><strong><em>Diagnostic Evaluation<\/em><\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">7<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Refer for prompt endoscopy with H. pylori testing if with combination of alarm features <strong>(A-I)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">8<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">If available, offer non-invasive <em>H. Pylori<\/em> testing for patients with no alarm features <strong>(A-I)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">9<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Offer upper abdominal ultrasound, blood chemistry complete blood count, and\/or electrocardiogram if another organic problem\/s is\/are considered <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">10<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">If non-invasive H. Pylori test is not readily available, start empiric therapeutic trial <strong>(A-I)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">11<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Offer endoscopy if symptoms did not resolve after <em>H. Pylori<\/em> eradication or 4-8 weeks after therapeutic trial <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">12<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Offer test and treat for <em>H. pylori <\/em>if symptoms did not resolve after 4-8 weeks of therapeutic trial, with a 2-week wash off-period from PPI <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" colspan=\"2\" width=\"601\"><strong><em>Pharmacologic Interventions<\/em><\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">13<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">For patients with ulcer- or reflux-like dyspepsia, offer proton-pump inhibitors for 4-8 weeks <strong>(A-I)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">14<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">For patients with dysmotility-like dyspepsia, offer a prokinetic for 1 week. PPI may be added and continued for 4-8 weeks. <strong>(A-I)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">15<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">For patients with unspecified dyspepsia, offer PPI for 4-8 weeks. Prokinetic may be added for 1 week. <strong>(A-I)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">16<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">For all symptom-based categories, offer antacids and\/or alginate as needed for immediate symptom relief <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">17<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Start <em>H. pylori <\/em>eradication therapy if <em>H. pylori<\/em> positive <strong>(A-I)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">18<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Consider H2-receptor antagonists for 2-4 weeks if with inadequate response to or unable to tolerate PPI <strong>(A-I)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">19<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">If unresponsive after 4-8 weeks of initial treatment, offer tricyclic antidepressants <strong>(A-I)<\/strong><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" width=\"601\"><strong><em>Non-pharmacologic Interventions<\/em><\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">20<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Discuss with patient the risk factors, lifestyle modification and possible complications of dyspepsia <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">21<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Explain the dose, frequency, intended effect, possible side effects of medications, and importance of adherence <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"37\">22<\/td>\n<td width=\"800\">Discontinue or replace dyspepsia-causing medications <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">23<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Offer counselling if with psychosocial concerns <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">24<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Elicit family members\u2019 lifestyle activities and offer modifications <strong>(A-III)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">25<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Consider community lifestyle activities <strong>(A-III)<\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" colspan=\"2\" width=\"601\"><strong><em>Patient Outcomes<\/em><\/strong><\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"37\">26<\/td>\n<td style=\"padding: 5px 5px 5px 5px; border: 1px solid #999999;\" width=\"800\">Patients must be educated about the diagnosis, its nature, risk factors and possible complications. The need to adhere to pharmacologic interventions, as well as lifestyle modifications must be emphasized.\u00a0 Control of symptoms, improvement of quality of life and functional status, and prevention of recurrence are the main therapeutic goals. <strong>(A-II)<\/strong><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>\u00a0<\/strong><\/p>\n<p>The complete recommendations per visit are outlined in Table 2.<\/p>\n<p><strong>Dissemination and Implementation<\/strong><\/p>\n<p>This guideline shall be disseminated and implemented at the clinic and organizational level.\u00a0 It will be published in the \u201cThe Filipino Family Physician\u201d journal, social media platforms and will be disseminated through Âé¶¹Ö±²¥ local chapters, training institutions and during the national convention. Non-FCM primary care physicians will also be reached through relevant agencies. It shall be included in the references required during training activities and national exams of accredited training institutions, in coordination with the Âé¶¹Ö±²¥ committee on Residency Training. It shall be incorporated in checklists for compliance in audits and QA cycles, with support from the Âé¶¹Ö±²¥ committee on Quality Assurance and that on Standards for Family Practice.\u00a0 Feedback on utility and applicability will be actively sought from the intended users and other stakeholders.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"_acf_changed":false,"footnotes":""},"categories":[14,18],"tags":[16],"class_list":["post-3192","abstract","type-abstract","status-publish","hentry","category-abstract","category-abstract_2021_vol59_issue2","tag-abstract"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/abstract\/3192","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/abstract"}],"about":[{"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/types\/abstract"}],"version-history":[{"count":3,"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/abstract\/3192\/revisions"}],"predecessor-version":[{"id":3195,"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/abstract\/3192\/revisions\/3195"}],"wp:attachment":[{"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/media?parent=3192"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/categories?post=3192"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/thepafp.org\/journal\/wp-json\/wp\/v2\/tags?post=3192"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}